This is a list of player transfers involving Premiership Rugby teams before or during the 2021–22 season.
The list is of deals that are confirmed and are either from or to a rugby union team in the Premiership during the 2020–21 season.
It is not unknown for confirmed deals to be cancelled at a later date.
On 20 June, Saracens were promoted to Premiership Rugby for the 2021–22 season after defeating Ealing Trailfinders in the RFU Championship promotion playoff.
[1] No team is relegated from the Premiership this season due to an increase in the number of teams in the Premiership for 2021–22 season.