Chris Brown (who previously called play-by-play for the Buffalo Bulls football and Buffalo Destroyers arena football teams before joining the Bills as a studio host) is the current play-by-play announcer.
During preseason, most games are televised on MSG Western New York per a rights deal between MSG and the team owners Terry and Kim Pegula and simulcasted on Buffalo's ABC affiliate, WKBW-TV channel 7 along with the stations of Nexstar Media Group elsewhere in upstate New York.
WKBW's agreement expires after the 2019 season, at which point WIVB-TV, as a Nexstar affiliate, will take over as the official broadcast home of the Bills.
Sunday night games, should the Bills ever be selected for one, air on NBC, whose Buffalo affiliate is WGRZ.
As of 2021, the broadcast team consists of Andrew Catalon or Rob Stone on play-by-play, Steve Tasker as color commentator, and Cynthia Frelund as sideline reporter.