A Middle Eastern teenaged girl and a mercenary, Canaan is dispatched by her unknown superiors to the city of Shanghai in the People's Republic of China where she meets up with Maria Ōsawa.
Now a photographer, Maria reunites with her friend Canaan after being saved from harassment during a trip to the Middle East years ago.
Their presence in Shanghai, however, has been greatly overshadowed by the upcoming NBCR International Anti-Terrorist Conference in the same city where Alphard, Canaan's hated rival, plans to stage a terrorist attack with her subordinates known as "Snakes".
The creation of Canaan was first announced in the November issue of Newtype magazine that 428: Shibuya Scramble would have an anime adaptation.
[10] Comp Ace magazine had announced on a flyer that its July issue will serialize Canaan's manga adaptation.