List of Houston Astros Opening Day starting pitchers

[3] Bobby Shantz started their first Opening Day game on April 10, 1962, against the Chicago Cubs at Houston's Colt Stadium and was credited with the win.

[4][5][6] Three different pitchers have each made five Opening Day starts for the Astros: J. R. Richard (1976–1980), Mike Scott (1987–1991) and Shane Reynolds (1996–2000).

Niekro and Don Wilson share the worst record in Opening Day starts with no wins and two losses each.

This makes the record of the Astros' Opening Day starting pitchers in home games 21 wins, 13 losses and ten no decisions (23–21 overall).

[8] In 2022, they set a modern Major League Baseball record by winning on Opening Day for the tenth straight season.

Roy Oswalt , the Houston Astros Opening Day starting pitcher for eight straight years, from 2003 through 2010.
The Houston Astros played 25 Opening Day games in the Astrodome between 1965 and 1999.
Nolan Ryan made three Opening Day starts for the Astros.
Minute Maid Park , previously called Enron Park and Astros Field, is the Astros' current home ball park , and the Astros have played seventeen Opening Day games there through 2024.