There are 22 Interstate Highways—9 primary and 13 auxiliary—that exist entirely or partially in the U.S. state of North Carolina.

As of January 2020[update], the state had a total of 1,410 miles (2,270 km) of Interstates and 70 miles (110 km) of Interstate business routes, all maintained by the North Carolina Department of Transportation (NCDOT).

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