The Knights Hospitaller operated a wide network of properties in the Middle Ages from their successive seats in Jerusalem, Acre, Cyprus, Rhodes and eventually Malta.
After the Ottoman conquest of Rhodes in 1522, the Knights made stops in Candia, Messina, Bacoli near Naples, and Civitavecchia.
The Order of Saint John in Sweden was founded in 1920 following the disruption of the Johanniter in Northern Europe during World War I.
The Order of Saint John in the Netherlands was created in 1946 in a similar development following World War II.
Johanniter International, a partnership of the four Protestant Orders of St. John and their national charities, was founded in 2000 and is headquartered in Brussels.