The series follows the Kiramagers, Earthlings chosen by the extraterrestrial genie princess Mabushina of the planet Crystaria, as they fight back against the evil Yodonheim Empire's invasion of Earth.
As the planet Crystaria is invaded by the Yodonheim Empire, King Oradin sends his daughter, Princess Mabushina, off-world with the five Kiramai Stones to continue the fight.
Over time, she recruits esports professional Tametomo Imizu, track-and-field athlete Sena Hayami, stunt actor Shiguru Oshikiri, and surgeon Sayo Oharu to become Kiramai Yellow, Green, Blue, and Pink and begin training under Muryo.
Despite excelling as a Kiramager, Sena finds her athletic career is falling short, so she receives help from Miki and Natsume Masaki of her sponsor company, SCRTC, to get back into shape.
However, Yodonna rigs her new training gear to explode should she stop running while her teammates are forced to confront the Yodon Army's latest Jamenshi.