The minister of the interior and kingdom relations (Dutch: Minister van Binnenlandse Zaken en Koninkrijksrelaties) is the head of the Ministry of the Interior and Kingdom Relations and a member of the Cabinet and the Council of Ministers.

The incumbent minister is Judith Uitermark of the New Social Contract (NSC) party who has been in office since 2 July 2024.

Regularly, a state secretary is assigned to the ministry who is tasked with specific portfolios.

The current state secretaries are Eddie van Marum and Zsolt Szabó.