List of Minnesota Twins first-round draft picks

The draft order is determined based on the previous season's standings, with the team possessing the worst record receiving the first pick.

[1] In addition, teams which lost free agents in the previous off-season may be awarded compensatory or supplementary picks.

[5] Catcher Joe Mauer (2001) is the only Twins first round draft pick to be elected to the Baseball Hall of Fame in 2024.

[3] Eddie Leon (1965), Dick Ruthven (1972), Jamie Allen (1976), and Tim Belcher (1983) all failed to sign with the Twins without the team receiving compensation.

[15] As a result, Lee and 3 other 1996 first-round picks who were Boras clients were granted free agency and he ultimately signed with the Arizona Diamondbacks.

A man in a left-handed batting stance wearing pinstriped gray pants, a black shinguard on his right leg, a dark blue baseball jersey, and a dark-colored batting helmet.
Joe Mauer, the Twins' first-overall selection in the 2001 draft, won an MVP, two Gold Gloves, three Silver Sluggers, and three batting titles.
A dark-skinned man running in a grey pinstriped baseball uniform with "MINNESOTA" on the chest in red.
Torii Hunter was one of four players drafted by the Twins' in the first round of the 1993 draft.
A man wearing eyeblack and a blue shirt with an interlocking "T" and "C" on the left breast.
Michael Cuddyer (1997) was drafted as a shortstop but has never played a major league game at that position. [ 17 ]
A man in a left-handed batting stance holding a black bat wearing a blue baseball jersey and grey pinstriped pants.
Denard Span's selection in 2002 was one of five times the Twins made the 20th pick of the draft.