The anime is directed by Takuya Igarashi and produced by Bones, Aniplex, Dentsu, Media Factory, and TV Tokyo.

[17] Reruns aired on TV Tokyo under the title Soul Eater: Repeat Show from September 30, 2010, to March 31, 2011.

[18] The English dub of the series aired on Adult Swim's Toonami programming block starting on February 17, 2013.

The first opening and closing themes for the first 12 episodes are "Counter Identity" by Unison Square Garden and "Ao no Kaori" (碧の香り) by Yui Makino.

The second opening and closing themes from episode 13 onward are "Ai ga Hoshii yo" (愛がほしいよ) by Shion Tsuji and "Northern Lights" by How Merry Marry.