The main characters in the show are Lee, Marc, Megan, Tony, Cal, Karen, Tami and Jerry.
While walking on the street, a truck almost hits Tony, but he throws it to the other side of the road and figures out that he has super strength.
The Spiez investigate when they discover that an anthropologist acting like a caveman plans to return the world into the dinosaur age.
They hurry to their hometown to finish destroying the dinosaurs and defeating the anthropologist just in time to get home before their parents arrive.
Lee, Marc and Tony find her with an army of skateboarders responsible for breaking down the buildings so they can create skateparks for themselves.
The leader of the clowns is named the Juggler who instead of using the security codes to free prisoners, uses them to enter WOOHP Headquarters and create a crazy circus there.
Villain: Tex (Jerry in disguise) Because he is a genius, Marc is promoted to WOOCSI, a new division of WOOHP that specializes in Crime Scene Investigations.
She drains the knowledge of the celebrities, including Marc, and uses it to get revenge on Jerry for being a goodie two-shoes brother and to take over WOOHP.
Jerry sends Marc and Tony to investigate, while Lee and Megan deal with a villain destroying a museum.
The three remaining Spiez set off to rescue their brother and all the other people from Crabby Bob who hopes to sink the entire world into the ocean and make it safe for all fish and crabs.
In the B-story, Marc must overcome his fear of heights, which he got from his mission against the Human Projectile (which is shown when Jerry hypnotized him).
After Alpha and Omega capture Marc and Megan, Lee and Tony take the head of OOPSIE, another spy agency, into custody for questioning.
The Spiez have to get Tony to forget about the fame, which he says turned out to be a 24hr job and wants to resign and stop Slick Mick from sending WOOHP HQ into the local lake.
After multiple failures Marc decides to borrow technology from WOOHP to help him win, but does not know the chip is from Techno Tommy.
When the Spiez get shrunken themselves they must find some way to reverse the gadget and get back to their normal size before Davey smashes them into oblivion.
Villain: Sherry Lewis (2) Absent: Karen Weather patterns begin to go haywire and cause snow all over the world.
The Spiez investigate and travel to a tropical island where they meet with Stony Falcon, who has changed from skateboarding to snowboarding.
Mel escapes from WOOHP prison and is now out to get the Spiez by making all the adults drink juice that gives them childish behavior.
After finishing up a mission, the kids try to return home, only to be detained by answering a distress call from a mysterious island.
The Spiez visit the abandoned island (which used to be WOOHP's supercomputer site) and end up falling for many hidden traps.
The Spiez discover she is trying to combine her DNA with plants, but this poses no threats as Brathwaite has no money to fund her research.
But when he arrives at the factory, Flaky Fructose, the owner, brainwashes him and the other winners and puts them under his control to eliminate his competition: breakfast cereal makers.
Meanwhile, after learning from Jerry that the residue the found matches the ingredients in the Super Spy Flakes, Megan, Lee and Marc come to Tony's aid and take Flaky down.
Their first mission is divided into two teams: Lee and Marc try to stop Termitator and Tony and Megan go to the lab to try to eliminate a crazy machine.
In the B-story, Tony wants more acceptance from his siblings, so he decides to imitate them and copy them, which annoys Lee, Marc and Megan.
Although they don't arrive in time to stop the kidnapping, they do find a clue: a piece of red rubber nose.
He has stolen the senses of humor of those who are much funnier than him, and plans to put on a successful show for an unsuspecting audience of people who rejected him to get revenge on them.
Taking advantage of this, Sherry helps Jerry remember his spy past but tricks him into thinking the Clark siblings are bad guys.
With the help of some clues, they eventually find out that Clucky, an actor who wore a chicken costume for the company Kooky Farms for 30 years, is behind the kidnappings.
He plans to get revenge on Kooky Farms for replacing him with another chicken as the mascot by controlling the kidnapped animals to regain his celebrity status.