Led by Ichigo Momomiya, the girls protect the earth from aliens who wish to "reclaim" it.

Broadcast on both TV Aichi and other TXN affiliates, the series premiered on April 6, 2002, and aired weekly until its conclusion on March 29, 2003.

[2] 4Kids Entertainment licensed the first 26 episodes of the series for the English-dubbed release in North America in 2004.

[9] The episodes use two pieces of theme music: "My Sweet Heart", performed by Rika Komatsu for the opening theme, and "Koi wa A La Mode", performed by the five voice actors who played the Mew Mews, for the ending.

The final 26 episodes were released in two DVD box sets in uncut, French dubbed format through AK Vidéo.