When the cases in volume 268 were decided the Court comprised the following nine members: Linder v. United States, 268 U.S. 5 (1925), involved the applicability of the Harrison Act.

Dr. Charles Linder prescribed the drugs to addicts in Oklahoma, which the federal government said was not a legitimate medical practice.

Linder appealed, and the Supreme Court overturned his conviction, holding that the federal government in this case had overstepped its power to regulate medicine.

In Pierce v. Society of Sisters, 268 U.S. 510 (1925), the Supreme Court overturned an Oregon statute requiring children to attend only public schools.

The decision significantly expanded coverage of the Due Process Clause of the Fourteenth Amendment to the United States Constitution to recognize personal civil liberties.

Gitlow v. New York, 268 U.S. 652 (1925), is a landmark decision, in which the Supreme Court held that the Fourteenth Amendment to the United States Constitution had extended the First Amendment's provisions protecting freedom of speech and freedom of the press to apply to the governments of U.S. states.