It is funded by the European and Developing Countries Clinical Trials Partnership (EDCTP) and operates out of the South African Cochrane Centre (Cochrane Collaboration) based at the South African Medical Research Council.
It is publicly owned and managed by a non-profit organization and is funded by an enabling grant from Australia's National Health and Medical Research Council (NHMRC).
Initially a non-public database, it was launched for the public as EU Clinical Trials Register in March 2011.
The DRKS is an open access, free of charge online register for clinical trials and is available both in English and German.
Clinical trial guidelines for South Africa are available at the Department of Health's official site.
[7] South Korea's registry is Clinical Research Information Service (CRiS) and available at https://web.archive.org/web/20101121001837/http://ncrc.cdc.go.kr/cris/index.jsp.
Originally ISRCTN stood for 'International Standard Randomised Controlled Trial Number'; however, the scope of the registry has widened beyond randomized controlled trials to include any study designed to assess the efficacy of health interventions in a human population.
It registers both observational and interventional trials and content is curated by a team of expert editors.
Clinical trials conducted in the United States are required to be registered in the registry.
[10] The registry traces back to the Health Omnibus Programs Extension Act of 1988 (HOPE or Public Law 100-607) which mandated the development of a database of AIDS Clinical Trials Information System.