The portrait medallion is a part of the ornamentation of the so-called Desiderius Cross, 9th-century processional crux gemmata currently preserved in Museo di Santa Giulia, Brescia, Italy.
[33] The peculiar hair style of the older woman is unknown in Roman portraiture, but can be found on some 3rd-century plaster mummy masks from Egypt.
[33][34] Howells (2015) summarizes the research into the Brescia medallion demonstrating its connection to contemporaneous Roman-Egyptian art (in particular the Fayum mummy portraits) as well as linguistic arguments supporting the authenticity of the artefact based on 18th century scholarship.
[35] Jás Elsner (2007) also contends that the Brescia medallion likely depicts a family from Alexandria, since the inscription is in the Alexandrian dialect of Greek, and provides possible dates ranging from the early-3rd to mid-5th century AD, before it found its way to Italy where it adorned a 7th-century cross.
In 1759, French antiquarian Anne Claude de Caylus wrote that contemporary Roman dealers were selling gold-glass reproductions to tourists who thought them original.