List of second overall NFL draft picks

Seven Heisman Trophy winners have been selected with the pick: Glenn Davis (1946), Billy Vessels (1952), John David Crow (1957), Reggie Bush (2006), Robert Griffin III (2012), Marcus Mariota (2014), and Jayden Daniels (2024).

13 have been inducted into the Pro Football Hall of Fame: Sid Luckman (1939), George McAfee (1940), Les Richter (1952), Bob Brown (1964), Tom Mack (1966), Randy White (1975), Tony Dorsett (1977), Lawrence Taylor (1981), Eric Dickerson (1983), Marshall Faulk (1994), Tony Boselli (1995), Julius Peppers (2002), and Calvin Johnson (2007).

[2] 13 have been inducted into the Pro Football Hall of Fame: Sid Luckman (1939), George McAfee (1940), Les Richter (1952), Bob Brown (1964), Tom Mack (1966), Randy White (1975), Tony Dorsett (1977), Lawrence Taylor (1981), Eric Dickerson (1983), Marshall Faulk (1994), Calvin Johnson (2007), Tony Boselli (1995), and Julius Peppers (2002).

[3] Seven Heisman Trophy winners have been selected at the spot: Glenn Davis (1946), Billy Vessels (1952), John David Crow (1957), Reggie Bush (2006), Robert Griffin III (2012), Marcus Mariota (2014), and Jayden Daniels (2024).

Notable draft busts selected include Lam Jones (1980), Tony Mandarich (1989), Blair Thomas (1990), Ryan Leaf (1998), Charles Rogers (2003), and Jason Smith (2009).