This list of the Mesozoic life of South Dakota contains the various prehistoric life-forms whose fossilized remains have been reported from within the US state of South Dakota and are between 252.17 and 66 million years of age.
Restorative model of the Late Cretaceous mammal
Alphadon
Mounted fossilized skeleton of the Late Cretaceous sea turtle
Archelon
Fossilized shell of the Late Cretaceous ammonoid cephalopod
Baculites
Restoration of the Late Jurassic sauropod dinosaur
Barosaurus
rearing to defend itself against a pair of the theropod
Allosaurus
Life restoration of the Late Cretaceous
Alligator
relative
Brachychampsa
Life restoration of a herd of the Late Jurassic sauropod dinosaur
Camarasaurus
Life restoration of the Late Cretaceous-Eocene choristoderan reptile
Champsosaurus
Life restoration of the Late Cretaceous mosasaurid
Clidastes
Fossil of the Early Cretaceous-Eocene shark
Cretolamna
Fossil of the Jurassic-Cretaceous cycad relative
Cycadeoidea
Restoration of the Late Cretaceous dromaeosaurid ("raptor")
Dakotaraptor
preying upon an ostrich dinosaur