The parish includes the market town of Sandbach, and the villages of Elworth, Ettiley Heath and Wheelock, and most of the listed buildings are in these settlements.
The most important listed structure in the parish are the two 9th-century Sandbach Crosses, which were recorded in the town in the mid-16th century and were reinstalled in the Market Square in 1816.
One of the earliest public houses in the parish is the Black Bear Inn, a timber-framed building of 1634 that is listed at Grade II*.
The Trent and Mersey Canal runs through the parish and several listed buildings are associated with it, including bridges, locks, mileposts, accommodation for canal workers, a stable and ticket office, and a warehouse.
More unusual listed structures include three war memorials, a drinking fountain and a telephone kiosk.