Kramer coined the term "cosmetic pharmacology", and in this book he discusses the philosophical, ethical and social consequences of using psychopharmacology to change one's personality.

"[3] Nuland said that Kramer has used his preliminary observations to hype unjustified assertions in trade books and on TV shows, orchestrated by professional publicists.

Kramer responded to this review, stating that Nuland " goes on tediously establishing his bona fides as an old-style doctor (trained by the ostensibly witty Dr. Bean, familiar with the story of serotonin, etc., etc.

"[4] The Kirkus Reviews described Listening to Prozac as "thoughtful questioning is supported throughout by case histories and meaty reports on recent research.... A wise and unflinching examination of the ramifications for society--and for the individual--when the capsule replaces the couch.

"[5] Daniel X. Freedman, former president of the American Psychiatric Association, wrote that Listening to Prozac “does not provide reliable directions for those in troubled quest of self or those seeking a clear introduction to the brain sciences and pharmacology.”[6]