"[6] The Little Desert "remains relatively undisturbed by human activity, even though in the earlier years of European settlement it experienced some industry in the way of grazing and woodcutting."

Although most internal roads within the National Park are only accessible by four-wheel-drive vehicles and some are closed during winter or after wet weather.

[4] Prior to the establishment of the park, small Aboriginal family groups camped along the Wimmera River.

During the Second World War the Central Block was used as a bombing and gunnery range and the remains of several concrete observation bunkers are still present.

Public outrage over the proposed subdivision resulted in the responsible minister's losing his safe seat in a by-election.

Brush-tailed possums and Grey kangaroos are common throughout the park, and lizards can be observed basking in the sun.

[11][12] The malleefowl is a rare bird found on the site and their protection was a contributory factor in the decision to preserve the area in 1968.