In September 1953, she was given her own series named Little Dot, drawn by Steve Muffati, joining Harvey's growing cast of child-oriented comedy characters.

Like most of the so-called "Harvey Girls", appearing also in the Richie Rich Girlfriends title, Dot reached her peak between the mid-1950s and the late 1960s, eventually eclipsing Little Audrey in terms of sales.

Consequently, as Dot became a virtual clone of Famous Studios' Little Audrey (which Harvey was licensing at the time), the 'Dotty' aspect was emphasized so that the two characters wouldn't appear too similar.

[3] Dot's obsessive nature presaged the development of Harvey's quirky child-friendly characters, many of which deviated from the Audrey model by incorporating fantasy elements (Hot Stuff, Spooky), or oddball behavior (Little Lotta).

Like her in-house contemporaries, Dot frequently found herself at odds with parents, teachers and other representatives of Bonnie Dell's adult population.