Little Flower Catholic High School for Girls is a Catholic high school in Philadelphia, Pennsylvania within the Archdiocese of Philadelphia.

It is named after Saint Therese de Lisieux and is located in the Hunting Park section of North Philadelphia.

Little Flower publishes one of the most award-winning high school newspapers in the archdiocese, The Theresian.

[citation needed] Little Flower High School consists of roughly 700 girls and 7 boys.

The boys are a part of Little Flower's ESOL Program (English for Speakers of Other Languages).