Grosse Pointe Woods-Shores Little League, Grosse Pointe Woods, Michigan (3) Bowling Green Eastern Little League, Bowling Green, Kentucky (3) The Great Lakes Region is one of ten United States regions that currently sends teams to the Little League World Series, the largest youth baseball competition in the world.

The remaining U.S. state that borders on the Great Lakes, Minnesota, is in the Midwest region.

(The Canadian provinces that border the Great Lakes have their Little League champions participate in a nationwide tournament, with the winner representing Canada in the International bracket at the LLWS.)

This expansion was originally scheduled to occur for 2021, but was delayed to 2022 due to the COVID-19 pandemic.

Italics denote the state is no longer a member of the Great Lakes Region.