"Little Miss Can't Be Wrong" is a song by American rock group Spin Doctors, released in October 1992 by Epic Records as the lead single from their debut album, Pocket Full of Kryptonite (1991).

Lead singer Chris Barron has stated that the song was inspired by his relationship with his stepmother, despite popular belief that it was written about an ex-girlfriend.

[3] Barron had a viral tweet in August 2019 about the song's creation, writing: "My stepmom told me I'd be a janitor [nothing wrong with that] and live in the basement of a school and play guitar for the rats.

[5] Alan Jones from Music Week rated it three out of five, writing, "This driving, economical song — vaguely reminiscent in execution to some of Steve Miller's material — should win support of rock radio.

It may not be a Top 20 hit, but should nibble at the lower end of the chart, and tee up their album A Pocket Full of Kryptonite.