Pocket Full of Kryptonite is the debut studio album by the American rock band Spin Doctors, released in August 1991.

The album initially sold a respectable 60,000 copies in late 1991 due to its growing hardcore fanbase, before several radio stations (including WEQX in Vermont) started playing the single "Little Miss Can't Be Wrong" in mid-1992.

[10] The combined strength of the single along with the follow-up "Two Princes" led to the album's peak at Nos.

The album's title is a quote from the opening track, "Jimmy Olsen's Blues", a humorous song sung from the point of view of Jimmy Olsen, a character in the Superman comic book series.

The album cover, showing a phone booth, refers to Clark Kent frequently ducking into a nearby phone booth to change into his Superman attire.