The creek flows east for a few miles, heading down into a valley between the two aforementioned mountains.

Plants inhabiting this area include oaks, birches, laurel, and other species.

[6] Little Shickshinny Creek flows through a gorge in Pennsylvania State Game Lands #260.

[8] An intake dam was built on Little Shickshinny Creek by the Pennsylvania Game Commission.

[5] The creek also passes through Pennsylvania State Game Lands #260, which has a trail leading to it.

[12] The creek's upper reaches are in the Pennsylvania State Game Lands Number 55.

[5] Habitats along Little Shickshinny Creek include mainly a Hemlock Palustrine Forest Natural Community, but also a red maple swamp, a highbush blueberry shrub swamp, and a dry oak-heath forest.

[5] Trees found directly on Little Shickshinny Creek and its tributaries include hemlock, black gum, and yellow birch.

Other plants found on the banks of the creek include Canada mayflower, rhododendron, cinnamon fern, royal fern, starflower, dwarf ginseng, skunk cabbage, pink lady’s-slipper, and partridge berry.