Littleborough and Saddleworth was a parliamentary constituency in Greater Manchester, England.

This Conservative-Liberal Democrat marginal was held by the Conservative Party at the three general elections of its existence.

The victorious MP on each of these occasions was Geoffrey Dickens, who was elected in 1979 for Huddersfield West (which was a predecessor seat to this constituency, however no part of it was added to this seat when it was created in 1983).

However, at a by-election called after Dickens' death in 1995, it was won by Chris Davies of the Liberal Democrats.

1983–1997: The Metropolitan Borough of Oldham wards of Crompton, Lees, Saddleworth East, Saddleworth West, and Shaw, and the Metropolitan Borough of Rochdale wards of Littleborough, Milnrow, and Wardle.