Biggle was celebrated in science fiction circles as the author who introduced aesthetics into a literature known for its scientific and technological complications.

Such notables as songwriter Jimmy Webb and novelist Orson Scott Card have written of the tremendous effect that his early story, "The Tunesmith", had on them in their youth.

He loved writing historical fiction set in late Victorian and Edwardian England.

These were followed by a series of stories featured in Alfred Hitchcock's Mystery Magazine starring Biggle's Victorian sleuth, Lady Sara Varnley.

[2] Biggle was the founding secretary-treasurer of the Science Fiction Writers of America and served as chairman of its trustees for many years.

He numbered many of these science fiction notables among his friends, and his article in the July/August 2002 Analog Magazine, "Isaac Asimov Remembered", was based in part on his personal recollections of that celebrity.