The Lloyd District is a primarily commercial neighborhood in the North and Northeast sections of Portland, Oregon, United States.

Adjacent neighborhoods are Eliot and Irvington to the north, Sullivan's Gulch (with which it slightly overlaps) on the east, Kerns on the south, and Old Town Chinatown (via the Steel and Broadway bridges over the Willamette) to the west.

Prior to urban renewal in the 1950s, this area was an African American residential community, including many who had lost their homes in the Vanport flood of 1948.

The area includes restaurants, shops, hotels, movie theatres, condominiums and apartments, and office buildings (the largest being the Lloyd Center Tower, standing at 20 floors and 290 feet).

TriMet buses and MAX trains provide frequent service in the district, as well as a commuter express bus route form Vancouver via C-Tran.