He made his first-team debut as a substitute in Rangers' 1–0 win at home to Kitchee on 14 August 2000, scoring the match winner in the 88th minute.

On 2 September 2007, Lo made his league debut for Kitchee against rivals South China, ending in a 2–1 victory.

On 23 September 2010, in the 6:0 win over HKFC, Lo was kicked in the head from goalkeeper Rudolf Karel Hollaender after scoring the second goal and had to be substituted.

[3] On 4 June 2018, it was reported that after ten years with Kitchee, Lo had signed with fellow Hong Kong Premier League side R&F.

[7] On 16 May 2021, in his 20th game for Rangers in the 2020–21 season, he scored a 40 yards volley goal in a HKPL match against Resources Capital.

On 19 June 2007, Lo made his international debut for the senior national team in the Preliminary Competition of 2008 East Asian Football Championship against Chinese Taipei.

[11] On 20 May 2012, Lo won his girlfriend Canmy's hand in marriage with 99 roses and a ring after Kitchee beat Rangers 4–1 and successfully defended its league title.