His most notable film roles include A Night at the Roxbury (1998), Scary Movie (2000), Freddy vs. Jason (2003), White Chicks (2004), The Predator (2018) and Cosmic Sin (2021).
Munro's first films include starring roles in two Moment of Truth movies: Stand Against Fear, as a high-school jock who uses his popularity for all the wrong reasons, and Abduction of Innocence, as the boyfriend-turned-kidnapper of a teenage lumber heiress.
He appeared as Peter Musevini, a time traveling patriarch of a genetically-enhanced Nietzschean race, in "Pride Before the Fall", the 100th episode of Andromeda.
He has collaborated multiple times with the Wayans family, starring in four of the films (Scary Movie, White Chicks, Little Man, and Dance Flick).
In 2022, Munro played the recurring character Detective Larry Fitzgibbon on the DC comics series Peacemaker.