After growing tired of living on the road, the band relocated to Winterville sometime in 1986, where they rented a small two-bedroom house, and used their meager savings to purchase an old Ampex 8-track tape machine and two microphones.

Although doing this had become a Butthole Surfers tradition, Locust Abortion Technician was one of their last recordings done in such a manner; on subsequent releases the band would go into the studio with more fully formed songs.

The Butthole Surfers regularly play songs from Locust Abortion Technician during their live concerts, including "Sweat Loaf", "Graveyard", "Pittsburgh to Lebanon", "U.S.S.A.

[8] The album received critical acclaim upon initial release, appearing in the year-end lists of noteworthy publications such as Melody Maker,[16] NME[17] and OOR.

The record veers from heavy Sabbath sludge (even parodying that band on "Sweat Loaf") to grungy noise rock to progressive guitar and tape effects to almost folky numbers in one big, gloriously schizophrenic mess.”[4] In 2018, Pitchfork included the album on their list of "The 200 Best Albums of the 1980s", adding, “From the John Wayne Gacy-indebted cover art to the turbid sounds within, the group's third LP took a chainsaw to hardcore, psychedelic rock, country blues, Black Sabbath, and, on closer “22 Going on 23,” the sound of mooing cows and the agonizing confession of a sexual assault victim.