Five married men share ownership of an upmarket loft, which they use to discreetly meet their respective mistresses.

When the body of a murdered woman is found in that loft, the men begin to suspect each other of having committed the gruesome crime, as they are the only ones with keys to the premises.

By 19 February 2009, Loft was the most successful Flemish film ever at the box office with at the time 1,082,480 admissions, passing the previous record holder, Koko Flanel (1990).

The Loft was completed in 2014 and stars Karl Urban, James Marsden, Wentworth Miller, Eric Stonestreet and Schoenaerts reprising his role from the original film.

In 2021, Netflix India announced an untitled Hindi remake of Loft directed by the director-duo Abbas Mustan, starring Sharman Joshi, Arjun Rampal and Bobby Deol.