It is located in the Karen Hills area, near the State's northern tip, just above an embayment on the Pilu River.

Myanmar's largest hydropower plant (built by the Japanese as war reparation) is located about 20 km (12 mi) east of Loikaw at Lawpita Falls.

As an Agent of the British government he was exercising control over the local Karenni Rulers, being supervised by the Superintendent at Taunggyi.

As with the rest of Kayah State, outsider access to Loikaw has been restricted post-independence, with special permits required to secure entry.

Due to increase demands, new two two-storey buildings were constructed with the 1.945 billion yen funding from Japan International Cooperation Agency (JICA).