Running between North Finchley bus station and University College Hospital, it is operated by Metroline.

However, following the opening of the Victoria line in 1969 it was cut back to its present terminus at Warren Street.

The London Transport Executive stated that the opening of the tube line had reduced the number of passengers travelling between Warren Street and Victoria.

[1] Upon being re-tendered, the route was retained by Metroline with a new contract commencing on 5 February 2005.

[2] On 15 June 2019, the route was shortened; its southern terminus became University College Hospital near Warren Street station, replacing the former southern terminus at Tottenham Court Road station.