Lone Oak is an unincorporated community and former city in McCracken County, Kentucky, United States.

Pepper, an early resident of the area, who constructed a gristmill near the intersection of Lovelaceville Road and what is now US Highway 45.

[1] On November 4, 2008, the citizens of Lone Oak voted 75–64 to dissolve the city.

[3] The area of the former city is split between the census-designated places of Hendron to the east and Massac to the west, with U.S. Route 45 (Lone Oak Road) serving as the boundary.

The Paducah city limits touch what had been the northeast corner of Lone Oak.

According to the United States Census Bureau, the city of Lone Oak had a total area of 0.2 square miles (0.52 km2), all land.