De Loonse en Drunense Duinen National Park (duinen = dunes) is a national park situated in the south of the Netherlands, between the cities of Tilburg, Waalwijk and 's-Hertogenbosch.

It has been designated as a national park since 2002.

It is 35 km2 (14 mile²) in area, and located in the municipalities of Loon op Zand, Heusden, and Vught.

The Loonse en Drunense Duinen consists of forests and very large dunes, creating an extraordinary microclimate.