A French naval squadron captured Lord Nelson off Sierra Leone on her sixth voyage, before she had embarked any captives.

[3] 1st voyage transporting enslaved people (1799-1800): Reportedly, Captain Hugh Stephens sailed from Liverpool on 7 March 1799, bound for West Central Africa.

They wounded two sailors; the rest escaped in the boats and made their way to Lord Nelson, leaving the ship in the rebels's hands.

The judge of the High Court of Admiralty awarded the plaintiff 10% of the estimated value of Trelawney, her cargo, and freight, approximately £10,000, plus the salvor's expenses.

[4] 2nd voyage transporting enslaved people (1800-1801): Captain John Wilson sailed from Liverpool on 13 November 1800, bound for the Windward Coast.

[5] Lord Nelson acquired captives at Grand Cape Mount and left Africa on 4 February 1801.

[9] 3rd voyage transporting enslaved people (1801-1802): Captain Francis Darnoult sailed from Liverpool on 3 September 1801.

[10][b] 4th voyage transporting enslaved people (1802-1803): Captain Isaac Westron sailed from Liverpool 31 August 1802.

[5] Lord Nelson left Africa on 30 January 1803 and arrived at the Bahamas on 23 March with 250 captives.

[12] 5th voyage transporting enslaved people (1804-1805): Captain Thomas Omen acquired a letter of marque on 11 July 1804.

[14] Lloyd's List reported on 8 April 1806 that a French squadron consisting of an 84-gun ship-of-the-line and three frigates had captured Lord Nelson, Trio, and the sloop-of-war HMS Favourite off the coast of Africa.