After graduating from Illinois State University, Loren Wiseman co-founded Game Designers' Workshop with Frank Chadwick, Rich Banner, and Marc Miller on June 22, 1973.

During this period he designed the wargame Pharsalus[5] (1977), and wrote the award-winning Twilight: 2000 role-playing adventure Going Home.

Wiseman helped Frank Chadwick, John Harshman, and Marc Miller design Traveller (1977).

[11][12] Loren had written "The City of Ascalon" for publication as part of the Dangerous Journeys RPG, but work was halted by the settlement GDW made with TSR.

He sold the rights to Donald Eccles, who later formed FGG Games, LLC in 2023 to publish Ascalon and other works.