Lori Ann Setton is an American biomechanical engineer noted for her research on mechanics and mechanobiology of the intervertebral disc, articular cartilage mechanics, drug delivery, and pathomechanisms of osteoarthritis.
She is currently the department chair as well as the Lucy and Stanley Lopata Distinguished Professor of Biomedical Engineering at McKelvey School of Engineering at Washington University in St. Louis.
Subsequently, she pursued graduate degrees under the tutelage of Professor Van C. Mow at Columbia University.
She joined the Department of Biomedical Engineering at Duke University as an assistant professor in 1995.
Her most noticeable work has documented the biological responses of cartilage and intervertebral disc to mechanical loading,[1] [2] [3] [4] [5] [6] understanding a role for collagen genetic mutations in onset of arthritis and intervertebral disc pathology,[7] [8] development of injectable hydrogels for articular cartilage repair,[9][10][11][12] and development of injectable drug delivery vehicles for fighting inflammation in musculoskeletal disease.