Los Amigos High School is located at the southeast corner of Newhope Street and Heil Ave and is one block east of Mile Square Park.

Recently the school installed several new classrooms the "A","B","C" and "D" portables to accommodate the increasing number of freshmen each year.

Since opening its doors in 1968, Los Amigos has been led by the following principals: Hal Butler, Ken Calkins, George Wilson, Connie Van Luit, Robin Patterson, Vicky Braddock, Amy Avina, and Todd Nirk.

[4] The vast majority of the Los Amigos student body is drawn from the communities of Fountain Valley and Santa Ana.

Los Amigos offers Regional Occupation Program (ROP) courses in the following disciplines: Art of Animation, Automotive Careers, Business Applications, Computer Aided Drafting, Construction Technology, General Office Clerk, Restaurant Careers, and Software Specialist.