Los Andes Province (Spanish: Provincia de Los Andes) is one of eight provinces of the central Chilean region of Valparaíso (V).

As a province, Los Andes is a second-level administrative division, governed by a provincial delegate who is appointed by the president.

Edith Quiroz Ortiz, appointed by president Piñera on April 22, 2010, was the first woman to hold the office of Governor of Los Andes.

The presidential provincial delegate appointed by president Gabriel Boric is Cristian Aravena Reyes, a Socialist.

[1] The province is composed of four communes (Spanish: comunas), each governed by a municipality consisting of an alcalde and municipal council: The province spans a landlocked area of 3,054.1 km2 (1,179 sq mi), the second largest in the Valparaíso Region.