Los Locos, also known as Los Locos: Posse Rides Again, is a 1997 Western film directed by Jean-Marc Vallée, written by and starring Mario Van Peebles.

It also stars Melora Walters, René Auberjonois, and Danny Trejo.

During the 1800s in the Wild West, a gunman by the name of Chance is hired to escort emotionally challenged people across the desert safely.

The film was originally conceived as an independently-assembled project by writer/producer Van Peebles.

After completion, Polygram, who had previously released Posse to moderate success, acquired the film for home video release, and in most territories sold it as a sequel even though it had no ties to the film and Van Peebles plays a character unrelated to his role in the earlier film.