[1][2] It follows the life of a bisexual[3][4] succubus named Bo, played by Anna Silk,[5][6] as she learns to control her superhuman abilities, help those in need, and discover the truth about her origins.

Over the top of the sequence and theme song is the voice-over monologue by the protagonist, Bo (Anna Silk), summarizing her story: Life is hard when you don't know who you are.

She began to feel "different" when she entered puberty and didn't know she was not normal until she accidentally killed her high school boyfriend by draining his life energy during her first sexual encounter.

During this hectic time, Bo develops a no-strings-attached lustful relationship with Ryan Lambert, a Dark Fae Loki playboy that in "Fae-nted Love" became unwittingly thralled by her when, during energy-drawing healing sex, her blood came into contact with deep scratches she made on his back.

Danger escalates when a human scientist convinces a despondent Lauren to join him in conducting scientific research in his private laboratory – all the while deceptively concealing his intent to harness Fae genetics for himself with the use of her expertise.

All the while, she is on a very personal mission to unlock the secrets of her origin and find her birth mother...Leading the Lost Girl cast is Anna Silk (Billable Hours, Being Erica) as Bo.

The gang of monster misfits and human helpers includes Kristen Holden-Reid (The Tudors) as Dyson, an inhuman cop involved in a love/hate relationship with Bo – he absolutely hates how much he loves her.

Navigating this complicated life with Bo is her human confidante and street-smart survivor, Kenzi (Ksenia Solo)...Writers include Michelle Lovretta; Peter Mohan; Jeremy Boxen; Emily Andras; and Pamela Pinch...A companion website for the series is being produced concurrently and will launch with the show to give viewers an unprecedented, interactive experience.

On the same date, a press release indicated that Lost Girl cast and crew would be making an appearance at Fan Expo Canada in Toronto on August 27–29, 2010, where they would be answering questions about the show and have promotional items available for audience members as well.

[45][46] Showcase renewed Lost Girl for a second season on November 12, 2010, announcing "record-breaking ratings" and the "number one scripted series for Adults 25–54 across all specialty channels" in Canada.

[10][47] Production on thirteen episodes for Season 2 began on May 17, 2011, with filming taking place at a Toronto soundstage and at locations in and around the city until September 22, for a targeted Fall 2011 premiere.

[64] As a lead-in to the premiere of Season 4, Showcase announced the streaming of a four-part original "webisodes" series on its Lost Girl website, with the first episode released on October 13, 2013.

In a pre-linear promotion of anticipated series, Showcase released the first episode of Part 2, "44 Minutes to Save the World", online on August 21, in advance of the broadcast premiere on September 6, 2015.

"...The challenge was to create a fun, sex-positive world that celebrates provocative cheesecake for everyone, without falling into base stereotypes or misogynistic (or misandristic) exploitation along the way...Bo has lots of sex, with men, women, humans, Fae, threesomes... and she's still our hero, still a good person worthy (and capable) of love, and that's a rare portrayal of female sexuality...It's also rare to have a female lead who is so honestly sexual, without judgment...I think the single element I will remain proudest of is just that we've been able to create and put out into the world a sex positive universe where a person's sexual orientation is unapologetically present and yet neither defines them as a character, nor the show as a whole...I felt it was crucial to also demonstrate that sex and romance aren't the only ways that Bo measures a relationship's worth, to give the show balance...Fans may have noticed that Kenzi clarified her hetero orientation at the end of ep 101...That line was necessary because...I was determined to protect their platonic-yet-epic BFF-ness, so I made sure it was written in as canon.

But there was another, simpler and more personal reason: I think friendship is the fifth element...So, hidden in amongst all the romance and cleavage and threesomes, the Lost Girl Bo and Kenzi relationship is my own little love poem to all the BFFs out there who do it right.

In an interview for The Huffington Post after the announcement by Syfy that it had renewed the show for a third season, Andras described what direction she would like to see Lost Girl go in the future: Into a world where a bisexual protagonist is non-news.

I'm so proud of the comedic ambitions of Lost Girl, that it's dedicated genre [fare] that doesn't take itself too seriously, but I also love exploring the shades of gray; the moral ambiguity of characters who may live forever and their relationships with mortals who will not.

[86] On March 10, 2013, after the Showcase broadcast of Fae-ge Against The Machine, Emily Andras participated in a special live question and answer session on Doccubus.com[87] with fans of the show and of Bo & Lauren.

The lead character, Bo, is a bisexual succubus[7] that survives, thrives, and heals by feeding on the chi (life force) of male and female humans, and Fae — either by drawing it out through their mouths, or by absorbing the energy created from sexual contact with them.

Filmed on the series' "Dal Riata" set, the live audience one-hour program hosted by Lost Girl writer Steve Cochrane featured behind-the-scenes footage and interviews with Anna Silk, Kris Holden-Ried, Ksenia Solo, Zoie Palmer, Rick Howland, K.C.

Moderated by Jay Firestone, Executive Producer of Lost Girl, it featured (in order of introduction): Rick Howland ("Trick"), Zoie Palmer ("Dr. Lauren Lewis"), Anna Silk ("Bo"), Kris Holden-Ried ("Dyson"), Ksenia Solo ("Kenzi"), and K.C.

[120][121] The premiere of Season 4 was preceded by Lost Girl: An Evening at the Clubhouse, a one-hour special featuring cast-on-cast interviews, webisode footage and a sneak peek.

[65] On October 12, 2011, Prodigy Pictures and Showcase announced on the show's official Facebook page that episodes of Lost Girl had become available for purchase and download from iTunes Canada.

[142][143] The live tweeting event was repeated on January 14, 2013, during the U.S. premiere of Season 3 on Syfy, with Anna Silk, Kris Holden-Ried, Ksenia Solo, Zoie Palmer, Rick Howland, K.C.

[148] Vladislav Tinchev, writer for the German site Serienjunkies wrote that the series would benefit from "revealing more background information about the represented world," rather than spend time on "clumsy action scenes".

"[149] In anticipation of its United States premiere, Brian Lowry of Variety wrote: "At first glance, Lost Girl looks like another one of those Canadian imports picked up mostly for financial reasons.

"[150] Writing for The New York Times, Mike Hale said: "Like other fantasy-tinged shows on Syfy and USA, it offers the minor pleasures of formulaic fantasy and weekly puzzle solving, though in a cheaper-looking and less original package than usual...."[151] In a post-premiere review for The Huffington Post, Mauren Ryan wrote: "No one can say there's been a dearth of genre-tinged programs on television in recent years.

The vampire boom of the mid-aughts was followed by the zombie bonanza of the last couple of years; all in all, we're awash in various undead and otherworldly creatures...But one of the reasons Lost Girl has made such a big impression on me...is because the Syfy show does what so many genre programs fail to do these days: It has fun with its premise...But don't expect Lost Girl to be perfect: Bo's universe can seem constricted at times, the weekly clients and monsters aren't always interesting and occasionally the storytelling has abrupt moments.

[21] In Season 2, the decision to edit an emotive scene between Bo and Lauren from "Scream a Little Dream" created controversy among LGBT fans of the show, resulting in the network being accused of insensitivity and censorship.

Lost Girl producers responded to the backlash by issuing a public statement on the show's Facebook page[156] explaining that the edits were done in-house, and not by Syfy, for "timing and not content."