In 1626, Gentileschi traveled to England at the request of the Duke of Buckingham, a collector interested in his art and who had previously acquired some of his works.

The canvas narrates the moment when the daughters, after finding shelter in a cave, make their father drunk with the intention of having carnal relations with him.

Lot rests drunk in the arms of one of his daughters, while the other, standing up, points with one hand towards the outside of the cave where they have taken refuge; we glimpse the mother turned into a pillar of salt, and in the distance Sodom in flames.

The two women express the sensuality of the imminent sexual encounter by displaying part of their torso, even insinuating the birth of the breasts.

The artist has chosen bright colors for the daughters' clothing: yellow and ultramarine blue; Lot's dress has been resolved in a crimson hue.