The series stars Dom DeLuise as bachelor Stanley Belmont who lives with his bossy mother (Kathleen Freeman), his sister Olive (Beverly Sanders) and her unemployed husband, Arthur (Wynn Irwin).

Lotsa Luck is based on the British ITV London Weekend Television series On the Buses.

[1] The show centers around Stanley's frustration with his lazy, mooching brother-in-law, Arthur, who refuses to get a job, dresses like a slob (usually unshaven and wearing a bathrobe), is constantly smoking and eats like a horse.

Stanley works at the lost-and-found department of the city bus company, supporting his entire family.

[2] On November 29, 2005, S'More Entertainment released all 22 episodes on DVD in Region 1 in a 4-disc set entitled Lotsa Luck – The Complete Series.