[2] Raised in Mheer in the Zuid-Limburg region of Limburg, de Beer studied singing and piano in her youth.
[4] She was a prizewinner in the Ton Lutz Awards in 2009 for grooste regietalent (greatest directing talent),[4] for her production of Hauptling Abendwind / Vent du Soir.
Outside of The Netherlands, de Beer directed the Bavarian State Opera's first full staging of Puccini's Il Trittico, in Italian, in December 2017.
[8] She has directed productions at the Bregenz Festival, the Aalto-Musiktheater (Essen), the Theater an der Wien,[3] the Münchener Biennale and Oper Leipzig.
[4] In October 2020, the Vienna Volksoper announced the appointment of de Beer as its next artistic director, the first woman ever named to the post,[9][10] effective 1 September 2022, with an initial contract of 5 years.