In gambling terminology lottery payouts are the equivalent of RTP (Returns To Players).
In the US, large lottery winnings generally are advertised as an annuity amount, paid in 20 or more installments; in most cases, a cash option is available.
In this sense, typical RTP or returns to player percentages will vary with the size of the jackpot.
It can happen that after several rollovers, RTP exceeds 100%, so that if one were to buy every single ticket they would likely make a profit.
(Actually achieving a net profit depends on: taxes; one's chances of sharing the jackpot with another player; and whether one takes the cash or annuity option.)