Clark won the first event of 1965, the South African Grand Prix and went on to take four more wins on the way to his second world championship.
Clark set fastest lap but retired his Climax-engined 33 while Hill drove the BRM-engined car to second place.
The 33's final World Championship race was the 1967 Canadian Grand Prix, where privateer Mike Fisher finished in 11th place.
Fisher also qualified the car for that year's Mexican Grand Prix, but engine problems prevented him from starting the race.
A driveable, detailed virtual recreation of the Lotus 33 is available in the '1965 F1 Mod' add-on for the Grand Prix Legends PC-based F1 racing simulation.