While a student at Deerfield High School, Manfredini worked at a hardware store and at a steel company as a welder.

[2] In 2006, he partnered with Frank DiGioia, President and CEO of Fort Productions, to create the news/magazine style home improvement and lifestyle show HouseSmarts.

[7] Manfredini has been host of satellite media tours representing companies such as The Wood Promotion Network,[8] 3M,[9] Marvin Windows and Doors,[10] Ace Hardware,[11] Skil Power Tools.

[12] Manfredini has sung the National Anthem at Wrigley Field, home of the Chicago Cubs, three times – once in 1998, once in 2001 [13] and once as a duet in 2009 with his producer, Lindsey Smithwick (formerly Kreutzer).

[15] On May 30, 2012, Manfredini guest starred in the Irish musical The Twelve Tenors for one night at the Riverfront Theater in Chicago.